paroxysmal nonkinesigenic dyskinesia 1

A dystonia that is characterized by attacks of dystonic or choreathetotic movements precipitated by stress, fatigue, coffee or alcohol intake or menstruation, and has_material_basis_in autosomal dominant inheritance of heterozygous mutation in the PNKD metallo

A dystonia that is characterized by attacks of dystonic or choreathetotic movements precipitated by stress, fatigue, coffee or alcohol intake or menstruation, and has_material_basis_in autosomal dominant inheritance of heterozygous mutation in the PNKD metallo-beta-lactamase domain containing gene on chromosome 2q35.

Signs and symptoms

• Paroxysmal choreoathetosis
• Torticollis
• Dysphagia
• Myokymia
• Paroxysmal dystonia
• Dysarthria
• Facial grimacing