persistent hyperplastic primary vitreous

info · Eye

A developmental vitreous disease that is characterized by leukocoria, strabismus and vision loss, caused by failure of primary vitreous and hyaloid vasculature to regress during embryological development.

Signs and symptoms

Ultra-low vision with no light perception
Esotropia
Leukocoria
Shallow anterior chamber
Corneal opacity
Remnants of the hyaloid vascular system
Persistent pupillary membrane
Microcornea
Hyphema
Retinal fold