Conditions / Other
Peutz-Jeghers syndrome
info · Other · ICD-10: Q85.89
An intestinal disease characterized by melanocytic macules of the lips, buccal mucosa, and digits; multiple gastrointestinal hamartomatous polyps; and an increased risk of various neoplasms that has_material_basis_in heterozygous mutation in the serine/threoni
An intestinal disease characterized by melanocytic macules of the lips, buccal mucosa, and digits; multiple gastrointestinal hamartomatous polyps; and an increased risk of various neoplasms that has_material_basis_in heterozygous mutation in the serine/threonine kinase STK11 gene on chromosome 19p13.
Signs and symptoms
- Hypermelanotic macule
- Intestinal bleeding
- Labial melanotic macule
- Bloody diarrhea
- Intussusception
- Multiple gastric polyps
- Hamartomatous polyposis
- Oral melanotic macule
- Abdominal pain
- Iron deficiency anemia
Also known as: Colonic hamartomatous polyp; Peutz Jeghers colon polyp; Peutz Jeghers polyp; Peutz-Jeghers polyp of small Intestine; gastric Peutz-Jeghers polyp