polycystic kidney disease 2

info · Genetic

A autosomal dominant polycystic kidney disease that has_material_basis_in autosomal dominant inheritance of mutation in the PKD2 gene on chromosome 4q22.1.

Signs and symptoms

Elevated circulating alkaline phosphatase concentration
Multiple renal cysts
Hepatomegaly
Elevated gamma-glutamyltransferase level
Elevated circulating alpha-fetoprotein concentration
Hypokalemia
Polycystic kidney dysplasia
Jaundice
Hepatic cysts
Recurrent urinary tract infections

Also known as: APKD2; PKD2; Polycystic Kidney Disease, Adult, Type II