polycystic kidney disease 6

An autosomal dominant polycystic kidney disease characterized by the development of multiple small renal cysts and progression to renal insufficiency or end-stage renal disease (ESRD) most often after the sixth decade that has_material_basis_in heterozygous mu

An autosomal dominant polycystic kidney disease characterized by the development of multiple small renal cysts and progression to renal insufficiency or end-stage renal disease (ESRD) most often after the sixth decade that has_material_basis_in heterozygous mutation in the DNAJB11 gene on chromosome 3q27.

Signs and symptoms

• Polycystic kidney dysplasia
• Hypertension
• Renal insufficiency
• Decreased glomerular filtration rate
• Hepatic cysts
• Stage 5 chronic kidney disease
• Gout