posterior amorphous corneal dystrophy

A stromal dystrophy that is characterized by irregular sheetlike areas of opacification with involvement of the Descemet membrane and, in some instances, alterations of the normal endothelial mosaic and that has_material_basis_in a chromosome 12q21.33 contiguo

A stromal dystrophy that is characterized by irregular sheetlike areas of opacification with involvement of the Descemet membrane and, in some instances, alterations of the normal endothelial mosaic and that has_material_basis_in a chromosome 12q21.33 contiguous gene deletion syndrome.

Signs and symptoms

• Hypermetropia
• Corneal dystrophy
• Ectopia pupillae
• Iris coloboma

Also known as: PACD; chromosome 12q21.33 deletion syndrome