primary ovarian insufficiency 1

info · Genetic

A primary ovarian insufficiency that has_material_basis_in premutations in the FMR1 gene on chromosome Xq27.3, within a region defined as POF1 (Xq26-q28).

Signs and symptoms

Premature ovarian insufficiency
Increased circulating gonadotropin level
Irregular menstruation

Also known as: FMR1-related primary ovarian insufficiency; Fragile X-associated primary ovarian insufficiency; premature ovarian failure 1