primary ovarian insufficiency 6

A primary ovarian insufficiency that has_material_basis_in heterozygous or homozygous mutation in the FIGLA gene on chromosome 2p13.

Signs and symptoms

• Female infertility
• Premature ovarian insufficiency
• Hypoplasia of the uterus
• Secondary amenorrhea
• Elevated circulating luteinizing hormone level
• Elevated circulating follicle stimulating hormone level
• Streak ovary
• Primary amenorrhea