primary ovarian insufficiency 8

A primary ovarian insufficiency that has_material_basis_in homozygous mutation in the STAG3 gene on chromosome 7q22.

Signs and symptoms

• Premature ovarian insufficiency
• Elevated circulating luteinizing hormone level
• Elevated circulating follicle stimulating hormone level
• Streak ovary
• Decreased serum estradiol
• Primary amenorrhea
• Ovarian neoplasm