Conditions / Genetic
primary pigmented nodular adrenocortical disease 1
info · Genetic
A primary pigmented nodular adrenocortical disease that has_material_basis_in heterozygous mutation in the PRKAR1A gene on chromosome 17q24.2.
Signs and symptoms
- Increased urinary cortisol level
- Increased circulating cortisol level
- Decreased circulating dehydroepiandrosterone concentration
- Osteoporosis
- Depression
- Osteopenia
- Anxiety
- Emotional lability
- Bruising susceptibility
- Agitation
Also known as: PPNAD1