progressive familial heart block type IA

info · Genetic

A progressive familial heart block characterized by autosomal dominant inheritance of cardiac bundle branch disorder that may progress to complete heart block that has_material_basis_in mutation in the SCN5A gene on chromosome 3p21.

Signs and symptoms

Prolonged PR interval
Dyspnea
Complete heart block with broad QRS complexes
Syncope
Sudden cardiac death
Sudden death
Complete right bundle branch block
Left anterior fascicular block
Left posterior fascicular block

Also known as: PFHB1A