Conditions / Mental health

Rett syndrome

info · Mental health · ICD-10: F84.2

A pervasive developmental disease that is characterized by normal early growth and development followed by a slowing of development, loss of purposeful use of the hands, distinctive hand movements, slowed brain and head growth, problems with walking, seizures,

A pervasive developmental disease that is characterized by normal early growth and development followed by a slowing of development, loss of purposeful use of the hands, distinctive hand movements, slowed brain and head growth, problems with walking, seizures, and intellectual disability.

Signs and symptoms

  • Seizure
  • Profound intellectual disability
  • Stereotypical hand wringing
  • Intermittent hyperventilation
  • Motor deterioration
  • Developmental regression
  • Hypotonia
  • Generalized hypotonia
  • Delayed ability to sit
  • Progressive microcephaly

Medications that may treat it

trofinetide

Also known as: Rett's disorder; cerebroatrophic hyperammonemia