Conditions / Genetic

sclerosteosis 1

info · Genetic · ICD-10: M85.2

A sclerosteosis that has_material_basis_in homozygous mutation in the SOST gene on chromosome 17q21.

Signs and symptoms

  • Nail dysplasia
  • Irregular menstruation
  • Large face
  • Headache
  • Prominent supraorbital ridges
  • Visual loss
  • Tooth malposition
  • Sclerotic vertebral endplates
  • Papilledema
  • Large sella turcica

Also known as: SOST1