Conditions / Genetic

short-rib thoracic dysplasia 9 with or without polydactyly

info · Genetic · ICD-10: Q87.5

An asphyxiating thoracic dystrophy that has_material_basis_in homozygous or compound heterozygous mutation in the IFT140 gene on chromosome 16p13.

Signs and symptoms

  • Poor head control
  • Thoracic hypoplasia
  • Trigonocephaly
  • Rod-cone dystrophy
  • Posteriorly rotated ears
  • Nephronophthisis
  • Clinodactyly of the 2nd finger
  • Short middle phalanx of finger
  • Absent middle phalanx of 2nd finger
  • Pancreatic cysts

Also known as: SRTD9; renal dysplasia, retinal pigmentary dystrophy, cerebellar ataxia and skeletal dysplasia