Silver-Russell syndrome

A physical disorder that is characterized by severe intrauterine growth retardation, poor postnatal growth, craniofacial features such as a triangular shaped face and a broad forehead, body asymmetry, and a variety of minor malformations.

Signs and symptoms

• Short middle phalanx of the 5th finger
• Cafe-au-lait spot
• Abnormality of the cardiovascular system
• Craniopharyngioma
• Downturned corners of mouth
• Hepatocellular carcinoma
• Congenital posterior urethral valve
• Delayed skeletal maturation
• Delayed cranial suture closure
• Blue sclerae

Also known as: Silver Russell Dwarfism