solitary median maxillary central incisor

info · Genetic

A tooth disease characterized by single deciduous and parmanent maxillary central incisor that may be isolated or occur with a range of other systemic anomalies that has_material_basis_in heterozygous mutation in SHH on chromosome 7q36.3.

Signs and symptoms

Prominent median palatal raphe
Decreased response to growth hormone stimulation test
Midnasal stenosis
Choanal atresia
Hypotelorism
Holoprosencephaly
Pyriform aperture stenosis
Short stature
Torus palatinus
Specific learning disability

Also known as: SMMCI; fused incisors; single central maxillary incisor; single median maxillary central incisor; single upper central incisor