Conditions / Genetic

spermatogenic failure 10

info ยท Genetic

A spermatogenic failure that is characterized by defects in the annulus or the ring-like structure located at the distal end of the flagellar midpiece the autosomal dominant inheritance of that has_material_basis_in mutation in the SEPT12 gene on chromosome 16

A spermatogenic failure that is characterized by defects in the annulus or the ring-like structure located at the distal end of the flagellar midpiece the autosomal dominant inheritance of that has_material_basis_in mutation in the SEPT12 gene on chromosome 16p13.

Signs and symptoms

  • Male infertility
  • Abnormal sperm morphology
  • Reduced sperm motility
  • Oligozoospermia

Also known as: SPGF10; Spermatogenic failure with defective sperm annulus