spermatogenic failure 101

info · Genetic

A spermatogenic failure characterized by male infertility due to nonobstructive azoospermia that has_material_basis_in homozygous or compound heterozygous mutation in the ATG4D gene on chromosome 19p13.

Signs and symptoms

Male infertility
Decreased serum testosterone concentration
Non-obstructive azoospermia
Abnormal serum estradiol
Abnormal circulating follicle-stimulating hormone concentration
Abnormal circulating luteinizing hormone concentration
Low semen volume
Abnormal circulating testosterone concentration

Also known as: SPGF101