spermatogenic failure 14

info · Genetic

A spermatogenic failure that is characterized by male infertility due to azoospermia with sperm maturation arrest in the spermatid stage that has_material_basis_in mutation in the ZMYND15 gene on chromosome 17p13.

Signs and symptoms

Round spermatid arrest
Male infertility
Elevated circulating follicle stimulating hormone level
Azoospermia
Abnormal circulating luteinizing hormone concentration
Abnormal circulating testosterone concentration
Abnormal prolactin level

Also known as: SPGF14