spermatogenic failure 2

info · Genetic

A spermatogenic failure that is characterized by azoospermia or severe oligozoospermia that has_material_basis_in homozygous or compound heterozygous mutation in the MSH4 gene on chromosome 1p31.

Signs and symptoms

Male infertility
Non-obstructive azoospermia
Oligozoospermia
Azoospermia
Abnormal circulating follicle-stimulating hormone concentration
Abnormal circulating luteinizing hormone concentration
Abnormal circulating testosterone concentration

Also known as: SPGF2