spermatogenic failure 25

A spermatogenic failure characterized by maturation arrest at the primary spermatocyte stage resulting in severe oligozoospermia or azoospermia, small testes, and infertility that has_material_basis_in homozygous or compound heterozygous mutation in the TEX15

A spermatogenic failure characterized by maturation arrest at the primary spermatocyte stage resulting in severe oligozoospermia or azoospermia, small testes, and infertility that has_material_basis_in homozygous or compound heterozygous mutation in the TEX15 gene on chromosome 8p12.

Signs and symptoms

• Male infertility
• Decreased testicular size
• Spermatocyte maturation arrest
• Non-obstructive azoospermia
• Cryptozoospermia

Also known as: SPGF25