spermatogenic failure 28

info · Genetic

A spermatogenic failure characterized by nonobstructive azoospermia and a Sertoli cell-only phenotype in testes that has_material_basis_in homozygous or compound heterozygous mutation in the FANCM gene on chromosome 14q21.2.

Signs and symptoms

Male infertility
Elevated circulating follicle stimulating hormone level
Decreased testicular size
Non-obstructive azoospermia
Elevated circulating luteinizing hormone level
Decreased serum testosterone concentration

Also known as: SPGF28