spermatogenic failure 34

A spermatogenic failure characterized by multiple morphologic abnormalities of the flagella, resulting in immotile spermatozoa and infertility that has_material_basis_in homozygous or compound heterozygous mutation in the FSIP2 gene on chromosome 2q32.1.

Signs and symptoms

• Irregularly shaped sperm tail
• Coiled sperm flagella
• Male infertility
• Reduced sperm motility
• Absent sperm axoneme central pair complex
• Absent sperm flagella
• Short sperm flagella

Also known as: SPGF34