spermatogenic failure 42

A spermatogenic failure characterized by multiple morphologic abnormalities of the flagella resulting in severly impaired sperm progressive motility and infertility that has_material_basis_in homozygous or compound heterozygous mutation in the TTC29 gene on ch

A spermatogenic failure characterized by multiple morphologic abnormalities of the flagella resulting in severly impaired sperm progressive motility and infertility that has_material_basis_in homozygous or compound heterozygous mutation in the TTC29 gene on chromosome 4q31.22.

Signs and symptoms

• Male infertility
• Reduced sperm motility
• Coiled sperm flagella
• Microcephalic sperm head
• Tapered sperm head
• Absent sperm flagella
• Short sperm flagella

Also known as: SPGF42