spermatogenic failure 43

A spermatogenic failure characterized by multiple morphologic abnormalities of the flagella resulting in absence of forward motility in spermatozoa and infertility that has_material_basis_in homozygous or compound heterozygous mutation in the SPEF2 gene on chr

A spermatogenic failure characterized by multiple morphologic abnormalities of the flagella resulting in absence of forward motility in spermatozoa and infertility that has_material_basis_in homozygous or compound heterozygous mutation in the SPEF2 gene on chromosome 5p13.2.

Signs and symptoms

• Absent sperm axoneme central pair complex
• Coiled sperm flagella
• Male infertility
• Reduced sperm motility
• Absent sperm flagella

Also known as: SPGF43