spermatogenic failure 45

A spermatogenic failure characterized by male infertility due to severe teratozoospermia with multiple morphologic abnormalities of the flagella and disruption of the axonemal complex and mitochondrial sheath that has_material_basis_in homozygous or compound h

A spermatogenic failure characterized by male infertility due to severe teratozoospermia with multiple morphologic abnormalities of the flagella and disruption of the axonemal complex and mitochondrial sheath that has_material_basis_in homozygous or compound heterozygous mutation in the DNAH2 gene on chromosome 17p13.1.

Signs and symptoms

• Coiled sperm flagella
• Male infertility
• Reduced sperm motility
• Absent sperm flagella
• Short sperm flagella

Also known as: SPGF45