spermatogenic failure 46

A spermatogenic failure characterized by male infertility due to asthenoteratozoospermia with multiple morphologic abnormalities of the flagella and disorganization of the axonemal and periaxonemal structures that has_material_basis_in homozygous or compound h

A spermatogenic failure characterized by male infertility due to asthenoteratozoospermia with multiple morphologic abnormalities of the flagella and disorganization of the axonemal and periaxonemal structures that has_material_basis_in homozygous or compound heterozygous mutation in the DNAH8 gene on chromosome 6p21.2.

Signs and symptoms

• Irregularly shaped sperm tail
• Coiled sperm flagella
• Male infertility
• Reduced sperm motility
• Absent sperm flagella
• Short sperm flagella

Also known as: SPGF46