spermatogenic failure 51

A spermatogenic failure characterized by severe asthenoteratozoospermia with multiple morphologic abnormalities of the flagella resulting in reduced to absent motility that has_material_basis_in homozygous or compound heterozygous mutation in the CFAP91 gene o

A spermatogenic failure characterized by severe asthenoteratozoospermia with multiple morphologic abnormalities of the flagella resulting in reduced to absent motility that has_material_basis_in homozygous or compound heterozygous mutation in the CFAP91 gene on chromosome 3q13.33.

Signs and symptoms

• Irregularly shaped sperm tail
• Coiled sperm flagella
• Microcephalic sperm head
• Reduced sperm motility
• Macrozoospermia
• Absent sperm axoneme central pair complex
• Absent sperm flagella
• Short sperm flagella
• Oligozoospermia

Also known as: SPGF51