spermatogenic failure 58

A spermatogenic failure characterized by multiple morphologic abnormalities of the flagella and immotile or severely reduced progressive motility of sperm that has_material_basis_in homozygous or compound heterozygous mutation in the IFT74 gene on chromosome 9

A spermatogenic failure characterized by multiple morphologic abnormalities of the flagella and immotile or severely reduced progressive motility of sperm that has_material_basis_in homozygous or compound heterozygous mutation in the IFT74 gene on chromosome 9p21.2.

Signs and symptoms

• Irregularly shaped sperm tail
• Male infertility
• Short sperm flagella
• Reduced progressive sperm motility
• Immotile sperm
• Oligozoospermia

Also known as: SPGF58