Conditions / Genetic

spermatogenic failure 65

info ยท Genetic

A spermatogenic failure characterized by male infertility due to asthenoteratozoospermia with severely reduced or absent progressive sperm motillity and multiple morphologic abnormalities of the flagella that has_material_basis_in homozygous or compound hetero

A spermatogenic failure characterized by male infertility due to asthenoteratozoospermia with severely reduced or absent progressive sperm motillity and multiple morphologic abnormalities of the flagella that has_material_basis_in homozygous or compound heterozygous mutation in the DHND1 gene on chromosome 11p15.4.

Signs and symptoms

  • Irregularly shaped sperm tail
  • Reduced progressive sperm motility
  • Male infertility
  • Reduced sperm motility
  • Abnormal sperm mid-piece morphology
  • Absent sperm flagella
  • Short sperm flagella
  • Coiled sperm flagella
  • Oligozoospermia

Also known as: SPGF65