spermatogenic failure 72

A spermatogenic failure characterized by multiple morphologic abnormalities of the sperm flagella, resulting in lack of sperm motility, that has_material_basis_in homozygous mutation in the WDR19 gene on chromosome 4p14.

Signs and symptoms

• Irregularly shaped sperm tail
• Coiled sperm flagella
• Reduced progressive sperm motility
• Male infertility
• Absent sperm axoneme central pair complex
• Absent sperm flagella
• Short sperm flagella

Also known as: SPGF72