spermatogenic failure 74

A spermatogenic failure characterized by nonobstructive azoospermia due to complete meiotic arrest at the spermatocyte zygotene or pachytene stage that has_material_basis_in homozygous mutation in the MSH5 gene on chromosome 6p21.33.

Signs and symptoms

• Male infertility
• Spermatogenesis maturation arrest
• Non-obstructive azoospermia

Also known as: SPGF74