spermatogenic failure 77

info · Genetic

A spermatogenic failure characterized by extreme oligozoospermia or azoospermia that has_material_basis_in homozygous or compound heterozygous mutation in the FKBP6 gene on chromosome 7q11.23.

Signs and symptoms

Male infertility
Elevated circulating follicle stimulating hormone level
Oligozoospermia
Multiflagellar spermatozoa
Cryptorchidism
Azoospermia
Abnormal circulating luteinizing hormone concentration
Abnormal circulating testosterone concentration

Also known as: SPGF77