spinocerebellar ataxia 19/22

An autosomal dominant cerebellar ataxia that is characterized by mild cerebellar ataxia, cognitive impairment, myoclonus and tremor.

Signs and symptoms

• Cerebellar atrophy
• Gait ataxia
• Dysarthria
• Saccadic smooth pursuit interruptions
• Nystagmus
• Hyporeflexia
• Gaze-evoked horizontal nystagmus
• Truncal ataxia
• Postural tremor
• Progressive cerebellar ataxia