spinocerebellar ataxia 25

info · Genetic

An autosomal dominant cerebellar ataxia that is characterized by ataxia and sensory neuropathy, has_material_basis_in repeat CAG expansion on chromosome 2p15-p21.

Signs and symptoms

Ataxia
Decreased number of peripheral myelinated nerve fibers
Cerebellar atrophy
Abolished vibration sense
Hearing impairment
Areflexia of lower limbs
Nystagmus
Strabismus
Dysarthria
Reduced visual acuity