Conditions / Genetic

split hand-foot malformation 1 with sensorineural hearing loss

info · Genetic · ICD-10: Q87.2

A split-hand/foot malformation characterized by split-hand/foot malformation and sensorineural hearing impairment that has_material_basis_in homozygous mutation in the DLX5 gene on chromosome 7q21.

Signs and symptoms

  • Sensorineural hearing impairment
  • Split foot
  • Split hand
  • Severe short stature
  • Scoliosis
  • Tapered finger
  • Frontal bossing

Also known as: SHFM1D; congenital deafness with split hands and feet