Conditions / Nervous system

Stiff-Person syndrome

info · Nervous system · ICD-10: G25.82

A movement disease that is of unknown etiology characterized by progressive rigidity.

Signs and symptoms

  • Vitiligo
  • Opisthotonus
  • Exaggerated startle response
  • Autoimmunity
  • Rigidity
  • Diabetes mellitus
  • Depression
  • Anemia
  • Proximal limb muscle stiffness
  • Anxiety

Also known as: Stiff-man syndrome; stiff man syndrome