subcortical band heterotopia

A congenital nervous system abnormality characterized by migration of neurons to ectopic locations in the brain where the neurons form areas that appear as band-like clusters of white tissue underneath the gray tissue of the cerebral cortex.

Signs and symptoms

• Lateral ventricle dilatation
• Agenesis of corpus callosum
• Global developmental delay
• Gray matter heterotopia
• Profound global developmental delay
• Severe intellectual disability
• Hydrocephalus
• Macrocephaly
• Polymicrogyria
• Seizure

Also known as: HeCo; band heterotopia; double cortex syndrome; heterotopic cortex; subcortical laminar heterotopia