syndactyly type 5

A syndactyly characterized by postaxial syndactyly of the hands and feet associated with metacarpal and metatarsal fusion typically affecting the 4th and 5th or the 3rd and 4th digits that has_material_basis_in heterozygous mutation in the HOXD13 gene on chrom

A syndactyly characterized by postaxial syndactyly of the hands and feet associated with metacarpal and metatarsal fusion typically affecting the 4th and 5th or the 3rd and 4th digits that has_material_basis_in heterozygous mutation in the HOXD13 gene on chromosome 2q31.1.

Signs and symptoms

• Absent distal interphalangeal creases
• Absent middle phalanx of the 3rd toe
• Ulnar deviation of the 5th finger
• Ulnar deviation of the 3rd finger
• Ulnar deviation of the 4th finger
• Short distal phalanx of finger
• Ulnar deviation of the 2nd finger
• 2-3 toe cutaneous syndactyly
• 4-5 metacarpal synostosis
• Camptodactyly of finger

Also known as: SDTY5; syndactyly with associated metacarpal and metatarsal fusion