Conditions / Syndrome
trichodontoosseous syndrome
info · Syndrome
A syndrome characterized by curly kinky hair at birth, enamel hypoplasia, taurodontism, thickening of cortical bones and variable expression of craniofacial morphology that has_material_basis_in heterozygous mutation in the DLX3 gene on chromosome 17q21.33.
Signs and symptoms
- Abnormal hair morphology
- Abnormal mastoid morphology
- Fragile nails
- Increased bone mineral density
- Microdontia
- Taurodontia
- Dolichocephaly
- Frontal bossing
- Widely spaced teeth
Also known as: TDO syndrome; tricho-dento-osseous syndrome