visceral heterotaxy 5

A visceral heterotaxy that is characterized by complete right-to-left reversal of the position of the major thoracic and abdominal organs and that has_material_basis_in heterozygous mutation in the NODAL gene on chromosome 10q22.

Signs and symptoms

• Dextrotransposition of the great arteries
• Atrial septal defect
• Pulmonary artery atresia
• Single ventricle
• Intrauterine growth retardation
• Abdominal situs ambiguus
• Dextrocardia
• Ventricular septal defect
• Abdominal situs inversus
• Asplenia

Also known as: Complete transposition; Laterality sequence; situs inversus; situs inversus viscerum