visceral heterotaxy 9

A visceral heterotaxy that is characterized by randomization of organ laterality, resulting in defects such as situs inversus and dextrocardia and that has_material_basis_in homozygous mutation in the MNS1 gene on chromosome 15q21.

Signs and symptoms

• Male infertility
• Dextrocardia
• Situs inversus totalis
• Recurrent otitis media
• Asplenia