Conditions / Other
von Willebrand's disease 1
info · Other · ICD-10: D68.01
A von Willebrand's disease characterized by quantitative partial deficiency of circulating VWF that has_material_basis_in heterozygous mutation in the VWF gene on chromosome 12p13.
Signs and symptoms
- Epistaxis
- Reduced factor VIII activity
- Menorrhagia
- Aortic valve stenosis
- Prolonged whole-blood clotting time
- Impaired platelet aggregation
- Gastrointestinal angiodysplasia
- Prolonged bleeding time
- Joint hemorrhage
- Reduced quantity of Von Willebrand factor
Also known as: VWD type 1; VWD1; von Willebrand disease type 1; von Willebrand disease type I