von Willebrand's disease 3

A von Willebrand's disease characterized by autosomal recessive inheritance of a severe quantitative defect or virtual absence of VWF in plasma, prolonged bleeding time, and more severe bleeding tendencies compared to the other types of von Willebrand disease

A von Willebrand's disease characterized by autosomal recessive inheritance of a severe quantitative defect or virtual absence of VWF in plasma, prolonged bleeding time, and more severe bleeding tendencies compared to the other types of von Willebrand disease that has_material_basis_in homozygous or compound heterozygous mutation in the VWF gene which maps to chromosome 12p13.

Signs and symptoms

• Reduced factor VIII activity
• Reduced von Willebrand factor activity
• Menorrhagia
• Abnormal bleeding
• Impaired platelet aggregation
• Prolonged bleeding time
• Bruising susceptibility
• Persistent bleeding after trauma
• Prolonged bleeding after surgery
• Epistaxis

Also known as: VWD type 3; VWD3; von Willebrand disease type 3; von Willebrand disease type III