Conditions / Syndrome
Werner syndrome
info · Syndrome
A progeroid syndrome characterized by premature aging and age-related phenotypes such as atherosclerosis, arteriosclerosis, cataracts, osteoporosis, soft tissue calcification, premature thinning, graying, and loss of hair, as well as a high incidence of some t
A progeroid syndrome characterized by premature aging and age-related phenotypes such as atherosclerosis, arteriosclerosis, cataracts, osteoporosis, soft tissue calcification, premature thinning, graying, and loss of hair, as well as a high incidence of some types of cancers and that has_material_basis_in mutations in the WRN gene, on chromosome 8.
Signs and symptoms
- Achilles tendon calcification
- Bird-like facies
- Body ache
- Hyperglycemia
- Elevated circulating alanine aminotransferase concentration
- Diabetes mellitus
- Osteoporosis
- Cataract
- Elevated hemoglobin A1c
- Premature graying of hair
Also known as: WS; Werner's syndrome; adult premature ageing syndrome; adult progeria