Conditions / Immune
WHIM syndrome 2
info · Immune
An immunodeficiency disease that is characterized by chronic neutropenia and myelokathexis, which is impaired neutrophil mobilization from the bone marrow and that has_material_basis_in homozygous mutation in the CXCR2 gene on chromosome 2q35.
Signs and symptoms
- Recurrent gingivitis
- Persistently decreased total neutrophil count
- Myelokathexis
- Severe infection
- Tetralogy of Fallot
Also known as: WARTS, HYPOGAMMAGLOBULINEMIA, INFECTIONS, AND MYELOKATHEXIS SYNDROME 2