X-Linked immunodeficiency 74

A T cell deficiency characterized by severe respiratory insufficiency in response to infection with the COVID19 coronavirus and impaired signaling through the TLR7 pathway that has_material_basis_in hemizygous mutation in the TLR7 gene on chromosome Xp22.2.

Signs and symptoms

• Severe SARS-CoV-2 infection
• Severe viral infection

Also known as: IMD74; TLR7 deficiency; X-linked immunodeficiency 74,COVID-19-related; respiratory insufficiency due to SARS-CoV-2 viral infection