X-linked spermatogenic failure 6

info · Genetic

A spermatogenic failure characterized by asthenoteratozoospermia with multiple morphologic abnormalities of the sperm flagella that has_material_basis_in hemizygous mutation in the USP26 gene on chromosome Xq26.2.

Signs and symptoms

Male infertility
Absent sperm axoneme central pair complex
Short sperm flagella
Coiled sperm flagella
Reduced progressive sperm motility
Microcephalic sperm head
Reduced sperm motility
Abnormal male external genitalia morphology
Recurrent bronchitis
Recurrent otitis media

Also known as: SPGFX6