X-linked spermatogenic failure 8

info · Genetic

A spermatogenic failure characterized by sperm with head and midpiece defects, deformed and detached acrosomes, and markedly reduced progressive motility that has_material_basis_in hemizygous mutation in the CYLC1 gene on chromosome Xq21.1.

Signs and symptoms

Reduced progressive sperm motility
Coiled sperm flagella
Male infertility
Oligozoospermia
Abnormal sperm head morphology

Also known as: SPGFX8