xeroderma pigmentosum group C

info · Syndrome · ICD-10: Q82.1

A xeroderma pigmentosum characterized by increased propensity to develop malignant melanoma that has_material_basis_in mutation in the XPC gene on chromosome 3p25.

Signs and symptoms

Telangiectasia
Actinic keratosis
Squamous cell carcinoma of the skin
Cutaneous photosensitivity
Defective DNA repair after ultraviolet radiation damage
Dermal atrophy
Keratitis
Basal cell carcinoma
Freckling
Hypopigmentation of the skin

Also known as: XP group C; XP3; XPC; XPCC; xeroderma pigmentosum III